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Tuesday 01 November 2005

[Neuropharmacological study of the joint action of verapamil and olanzapine on the content of neurotransmitters in Wistar rat brain structures]

By: Kudrin VS, Klodt PM, Gulieva ST.

Eksp Klin Farmakol 2005 Nov-Dec;68(6):12-4

The effects of jointly administered olanzapine and verapamil on the level of neurotransmitters and their metabolites in Wistar rat brain structures have been studied. Verapamil (i) produces a statistically significant decrease in dopamine and serotonin turnover increased by olanzapine injections and (ii) increases the norepinephrine content in all the brain structures studied.

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