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Friday 01 February 2002

Olanzapine-induced agranulocytosis: a case report and review of the literature.

By: Tolosa-Vilella C, Ruiz-Ripoll A, Mari-Alfonso B, Naval-Sendra E.

Prog Neuropsychopharmacol Biol Psychiatry 2002 Feb;26(2):411-4

The novel antipsychotic olanzapine has structural and pharmacological properties similar to clozapine. Until recently, no haematological toxicity has been reported with olanzapine use and it was expected to be a safer alternative. The authors report a case of agranulocytosis induced by olanzapine and reviewed the 11 cases reported in the literature.

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